Objective: To assess the diagnostic accuracy of color-power Doppler ultrasonography in differentiating malignant from benign cervical lymphadenopathy.
Methods: 42 lymph nodes in 42 patients with cervical lymphadenopathy were evaluated by color-power Doppler ultrasonography based on the morphological patterns of vascularity. Results were compared with histopathologic diagnoses.
Results: The patients were lüstopathologically confirmed to have metastasis (n=20), lymphoma (n=8), tuberculosis (n=3) and benign reactive lymphadenitis (n=ll). Twenty eight nodes were confirmed to be malignant and 14 were benign. According to findings on color-power Doppler ultrasonography, 27 lymph nodes were malignant, 15 lymph nodes were benign. Sensitivity and specificity of color-power Doppler ultrasonography were 89% and %85 respectively.
Conclusion: Color-power Doppler ultrasonography was useful in differentiating benign from malignant cervical lymphadenopathy with high diagnostic accuracy.

Objective: We aimed to assess the effects of the combination of cisplatin + paclitaxel (taxol) in patients with epithelial ovarian cancers
Material and Method: 13 patients with stage IV epithelial ovarian cancer who followed up more than 6 months in our clinic were evaluated retrospectively.
Result: The avarage age is was 54 (29-72). For their age groups; 7.6% of patients in 21-30, 30.7% of patients in 41- 50, 23% of patients 51-64 and 38. 4% of patients in 65+ age groups. All of the patients were with stage IV (FIGO). Serum Cal2-5 level was high in 61.5% of patients. Debulking surgery was performed 11 of patients. All of the patients were received chemotherapy regimens which involved cisplatinum (75 mg/m2) and paclitaxel (175 mg/m2), D1, every 21 days, total of 6. cycles. None of patients had haematologic and non- haematologic toxicities. Median survival was 14.6 months and 2-years sürvival was 23 months.
Conclusion: The combination of Cisplatinum and Taxol which, is the standart treatment of ovarian carcinoma is effec¬tive and less toxic regimen. The age of patient and the stage of disease are the most important prognostic factors.

Objective: In this study we evaluated the results of treatment and prognostic factors in endometrium carcinoma.
Material and Methods: 107 endometrum carcinoma patients, who were followed up for more than 6 months in our clinic have been evaluated. 58 of these patients were stuied in accordance with stages, histological subtype and treatment they received. Also their survivals were taken under our study.
Results: Avarage age of the partients were calculate 58.3 (27-80) with following details; 1.7% of patients in 21-30, 3.4% of patients in 31-40, 18.9% of patients in 41-50, 29.3% of patients in 51-60, 46.5% of patients in 61+ age groups. Acording to their histopathological status; adeno Ca: 42 patients, papiller seroz adeno; Ca 3 patients, aclenosquamous Ca 9 patients, mixt Ca; 6 patients, leiomyosarcoma; 2 patients. Avarage Survival period were found to be 44.7 months, 5 year-survival was 36% and 33 patients are still ob- sereved to be disease free of carcinoma.
Conclusion: Grade is rather important in Endomerium Car¬cinoma.. Stage and Grade are 2 both determining prognostic factors in this carcinoma. The incerase in Grade cause increase in local niiks and reduces survival.

Objective: The aim of this study was to determine whether color and power doppler twinkling artifacts could be considered an additional diagnostic sonographic feature of urinary tract and gallbladder calculi. Material and methods: 40 patients with at least 1 urinary tract calculi and ancl 15 patients with at least 1 gallbladder calculi on sonography were examined with color doppler sonography. Examinations included grayscale, color doppler, power doppler and spectral doppler.
Results: A color artifact was present within and/or distal to 55 urinary tract calculus (% 84). Close vertical bands were detected in the spectrum display. 33 gallbladder calculi showed twinkling artifact (% 94).
Conclusion: Color and power doppler twinkling artifacts from urinary tract and gallbladder calculi occur frequently and may be considered an additional sonographic feature of urinary tract and gallbladder calculi.

Between 1991-1995 years, 25 patients with skin hemangioma applied to Istanbul University, Institute of Oncology for the treatment. These patients were retrospectively analyzed. Radiation therapy for the treatment of skin hemangiomas is spared for the conditions that threating patient life and organ function and if the alternative treatments are unsuccesfull. Mean age of the analyzed patients with skin hemangioma is 4 years old (1 mounth-52years). As a sex, 19 patients are female and six patients are male. All of the skin hemangioma patients applied with skin redness and color changes. %68 of the skin hemangiomas were localized to face region, %/6 trunk and %16 upper extremity. 18 patients with skin hemangiomas were not treated, they were only followed. Three patients were treated with surgery, two patients with sclerosis, one patient with radiotherapy and other one with interferon. All of the treated patients improved and responded to treatment. %6 of the followed patiens improved completely, %56 partially. %32 of the lesion of the followed patients were stabil at the end of the follow. Progression of the lesion was seen at %6 of the followed patients.

Objective: The aim of this study was to compare the effects of propofol and sevoflurane anaesthesia on renal and hepatic function tests and recovery characteristics in long lasting surgeries.
Study design: After the approval by the Medical Ethic Committee of the hospital, 36 patients in ASA l-II physical status were randomized two groups. Anaesthesia was induced with propofol and atracuriurn and maintained with propofol infusi¬on (4-8 mg/kg/h) in Group P and with sevoflurane (2-3%) in Group S. Blood urea nitrogen, serum creatinin, AST, ALT levels were determined preoperatively, every 2 hours peroperatively, 30. min and 24 th hours postoperatively. As recovery characteristics time until eye opening, response to verba! commands, orientation-cooperation time were evaluated.
Results: Anaesthesia time was 349.7 minutes in Group P and 355.5 minutes in Group S. Laboratory values were similar between groups. There was not any significant difference between preoperative and postoperative values. Time until eye opening and response to verbal commands were shorter in Group P than Group S, but the difference was not significant. Orientation-cooperation time was statistically longer in Group S than Group P.
Conclusion: Propofol or sevoflurane has not any significant effect on liver or renal function tests, but recovery was faster with propofol in patients undergoing long lasting surgeries.

Objective: The aim of our study was to evaluate the accuracy of helical CT in the preoperative assessment with suspected pancreatic cancer using surgical and histopathologic correlation. We prospective!)’ evaluated the imagine findings to determine of pancreatic tumor and one of the signs of unresectability, peripancreatic vasculer encasement with tumor.
Material and methods: 15 patients with suspected pancreatic cancer underwent preoperative evaluation and staging with helical CT (3-mm collimation for arterial and pancreatic phase, 5-mm collimation for portal phase), iodinated contrast material was injected IV (¡00 mL at a rate of 3 niL / sec); acquisition began at 25 sec during the arterial phase, at 50-60 sec during the pancreatic phase and at 80 sec during the portal phase. Two radiologist prospectively evaluated the imaging findings to determine the precense of pancreatic tumor and signs of unresectability (vascular encasement). The degree of tumor-vessel contiguity was recorded for each patient (no contiguity with tumor, contiguity of <50 %, or contiguity of >50 %).
Results: 15 patients were surgically explored. Curative resections were attempted in 7 patients and were successful in 5. The positive predictive value for resectability was (517) 71%. 2 patients considered resectable on the basis of CT findings were found to be unresectable at surgery because of vasculer encasement. We found that the overall accuracy of helical CT as a tool for determining whether a pancreatic cancer was resectable was 87% (13115) patients).
Conclusion: Helical CT is a useful technique for preoperative staging of pancreatic cancer.

Objective: To investigate the antibiotic resistance of 1080 staphyloccocal strains isolated from wound specimens sent to the microbiology laboratory by different clinics at Sisli Etfal Training and Research hospital between 1999-2002. Study Design: The identification of bacteria was performed by colony morfology, growth and gram staining features, catatase and coagulase tests. The antibiotic resistance of these strains to methicillin, sefazolin, erythromycin, tetracycline, gentamicin, amikacin, ciprofloxacin, TMP/SXT was investigated according to NCCLS criteria by Kirby-Bauer disc diffusion method. The susceptibility to Fusidic acid was performed according to the criteria of Comité de L’antibiogramme de la Société Française de Microbiologie.
Results: Out of the isolated staphyloccocal strains 670 (62%) were S. aureus and 410 (38%) were coagulase negative staphylococci. Among S.aureus strains 260 (38%) and 220 (53%) of coagulase negative staphyloccocal strains were methicillin resistant. The antibiotic resistance rate to the tested antibiotics was higher among the methicillin resistant strains. Vancomycin resistance was not found. The most active antibiotics against methicillin resistant strains were TMP/SMX, fusidik Asit, amikasin, ciprofloxacin, gentamicin.
Conclusions: It seems that in staphyloccocal infections developing in hospitals, besides methicillin resistance, multiple drug resistance continues to be a serious problem in our hospital.

In treatment of idiopathic thrombocytopenic purpura (ITP) steroids, immunosuppresive agents and splenectomy is used to increase the platelet count. Reactive thrombocytosis is defined as an increase in platelet count above normal secondary to the presence of various conditions such as infection, trauma and malignancy. In the literature occurence reactive thrombocytosis in the setting of ITP has rarely been reported.

Pigmented villonodular synovitis ( PVNS ) is a benign, proliferative disease of the synovial membrane of joints, tendon sheaths, and bursas. It is almost always monoarticular and the knee is the most commonly affected joint, hi our case report, we have presented an extensive PVNS of the right knee joint in a 53 year ohl male patient and discussed clinical appearance, pathology, treatment and the value of the magnetic resonance imaging in the diagnosis of this pathologic condition.

Pemphigus vulgaris is a rare autoimmune disorder characterized by bullae appearing upon normal skin or mucous membranes. Skin lesions of pemphigus vulgaris present clinically typical bullae formation and ulceration. Most of the lesions start initially in the oral mucosa. Other mucosal involvements are conjunctiva, pharynx, larynx, oesophagus, urethra, vulva and cervix. We present the case of a 72 year old man with pemphigus vulgaris involving external ear mucosa.

Esophageal atresia is often associated with anomalies of other systems. It is also a part of VACTERL association. However, phocomelia has not been reported with esophageal atre¬sia before. In this case report, we present a female newborn with review of the literature that had esophageal atresia, distal tracheoesophageal fistula, phochomelia and suspicious pulmoner hypoplasia.