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Objective: Being the main death cause and medico-social problems of the disease makes statistics of cancer have become more important.
Study Design: We aimed to participate with this study to the cancer statistics of our country by doing a retrospective research of the patients who applied to The Department of Radiation Oncology of Þiþli Etfal Training and Research Hospital to determine catchment area by sorting them to their dwelling, sex, age, diagnosis and social guarantee.
Results: 20.467 patients have applied to our clinic between 17.09.1984 and 24.10.2001. Ratio of women/men was 0.59. Frequently seen age group was between 61 and 70. The first 3 countries of which the most the patients came from: Istanbul (n=2307,15,7%), Kastamonu (n=670,4,5%) and Sivas (n=654, 4,4%).
Conclusions: After 1984 the increase of clinics reputation, using new radiation instruments, increase in the quality of equipment and number, multidiciplinary work rised the patient numbers. Being a goverment hospital and applying surgery, radiotheraphy and chemotherapy without a fee to all social security associations patients who have cancer is an important factor.

Objective: Lumbar puncture (LP) is a method which applied to examine the cerebrospinal fluid. LP is used in diagnose of variable diseases (infections, tumors, intracranial bleeding...i. e.) and to measure the intracranial pressure. As it’s an invasive procedure parents have doubts and anxiety towards LP.
Study Design: A study was carried out to evaluate parents’ attitude and doubts about the lumbar puncture procedure; causes and solutions to these doubts. Parents of 90 children ever applied LP before was enlisted to the study in April 2006-October 2006. A questionnaire was filled by doctor after interview with one of the parents (usually mother). The questionnaire was consist of child’s indication for LP, sociocultural and demographic data about the parents, their initial reaction to the procedure, doubts about LP and thoughts after doctors talk to persuade. Charts were formed about the data we collected and the results evaluated with the SPSS 11. 0 statistical program.
Results: Most of the children’s indication for LP was CNS infections (%54.4), and some of them was fever of unknown origin (%22.2). %51.1 of the parents approved LP in the first hand, %46.6 of them were first denied but persuaded after the interview with the doctor. Paralysis was the most common (%60) doubt.
Conclusions: Parents tend to deny LP in the first hand; this situation is a problem preventing the diagnosis of diseases like CNS infections and intracranial bleeding which are life threatening. We have to acquaint the families and the community about the procedure by media, not to delay the diagnosis of serious diseases.

Objective: In this study, the effects of fentanyl and remifentanyl on the surgical stress response in patients undergoing cholecystectomy operation were compared.
Study design: 35 patients with ASA I-II physical status undergoing cholecystectomy were included in this study. The same general anaesthesia was given to patients which were double blind randomly divided into two groups. Group F (n=18) had Imcglkg fentanyl and until 20 seconds before the end of surgery lmcg/kg/h fentanyl was infused. Group R (n=17) had lmcg/kg remifentanil and until the end of surgery 0. 25mcg/kglmin remifentanyl was infused. MABP, HR values and blood cortisol, insuline, glucose, ACTH and GH levels were measured in four periods: 1. before the induction of anaesthesia, 2. before the surgical incision, 3. 10 minutes after the incision and 4. 20 minutes after extubation.
Results: During 2. and 3. period MABP, HR values were lower in Group R compared with Group F (p<0.05) and blood cortisol level was lower during 2. and 3. period in comparison with the first period. (p<0.001) There was no difference in the other stress parameters between the 2 groups
Conclusion: During cholecystectomy, remifentanyl provided more stable hemodynamics compared with fentanyl. There was no difference in stress response between the 2 groups and neither remifentanyl nor fentanyl was able to abolish stress response.

Objective: In our study we aimed to investigate the effectiveness of basal infusion added to bolus dose for patient controlled analgesia (PCA) for postoperative pain management.
Study design: 36 patients undergoing abdominal hysterectomy under general anaesthesia were randomized to three groups after standart anaesthetic procedure. In Group I bolus dose regimen, in Group II bolus dose+low basal infusion rate, in Group III bolus dose+high basal infusion rate were used for PC A. Postoperative pain evaluation(with Verbal Rating Scale-VRS-), respiration rate, sedation score were recorded at I., 2., 4., 8., 12. and 24. hours postoperatively. Total analgesic consumption for 24 hours was calculated. Side effects were observed.
Results: VRS was higher in Group I than Group II and Group III and respiration rate was lower in Group II and Group III than Group I. But these differences were not statistically significant (p>0.05). Sedation score and total analgesic consumption were significantly higher in Group III than Group I (p<0.05). Gastrointestinal side effects were more frequent in Group II and Group III than Group I.
Conclusion: We concluded that basal infusion added to bolus dose has not provide a significant superiority to bolus dose alone when used with PCA for postoperative pain management. Also side effects, mainly respiratory depression, can be associated with the increased total analgesic consumption caused by basal infusion.

Although double-J ureteral stents have been used routinely in urological practice for a long time, more recently, in parallel with the spread of indications the rate of complications has been on the rise. One of the most serious complications is stent encrustation. In this paper, the case of a 37 year -old patient who has flank pain, dysuria, frequency and macroscopic hematuria is evaluated. Following anemnesis, physical examination and screening test, evidence is presented with respect to right a functional kidney and bladder stone arising from long-standing double-J ureteral stent.

Honey which is produced in Brazil, Japan, Nepal and The Black Sea Region of Turkey is also known as the ‘mad honey’ by Turkish people and contains Rhododendron ponticum nectar, which is known to cause severe bradycardia and hypotansion. Grayanotoxin I, also known as andrometoxin, is only produced by Ericaceae plants and thought to be the compound which is responsible for the poisoning. Typical toxicat ion symptoms are assosieted with gastrointestinal system and sometimes may cause life-treatening severe bradycardia and hypotension. Here we present a patient who admitted to our emergency department with the symptoms of poisoning after the with the black sea honey.

Objective: Lymphoma of prostate is an uncommon disease. We report a case of prostate lymphoma.
Methods/Results: A 60 year-old male patient was referred to the Urology department with a clinical picture of prostatism. Biopsy was performed, and pathology revealed a primary prostate lymphoma. The patient was referred to Radiation Oncology Clinic. He received 6 cycle CHOP chemotherapy and external pelvic radiotherapy. I year later inguinal lymph node metastases was detected. He received 6 cycle second line VEBEP chemotherapy. The patient is currently followed by regular visits to Radiation Oncology Clinic.
Conclusions: Of the cases reviewed, mean age at diagnosis was 57 years. Clinical behavior was with prostate symptoms, with or without acute urinary symptoms and sometimes manifestations of renal failure due to obstructive uropathy, as well as general symptoms (astenia, anorexia, weight loss). PSA values remain unaltered in prostate lymphoma patients. Histologic diagnosis may be made by transrectal prostate biopsy Ultrasound and CT scan are of great utility for diagnosis of both local and distant tumors. From a therapeutic point of view, surgery for the obstruction of the lower urinary tract (TUR or retropubic prostatectomy) may be necessary, as well as the chemotherapy and radiotherapy.