ORIGINAL RESEARCH | |
1. | D-dimer levels in etiological diagnosis of ischemic stroke and relationship the prognosis Zahide Mail Gürkan, Dilek Necioğlu Örken, Ülgen Yalaz Tekan, Lale Gündoğdu Çelebi, A. Zeynel Tak, Hulki Forta, Nezaket Eren doi: 10.5350/SEMB2013470101 Pages 1 - 4 Background: Objective-Ischemic stroke is a disease with a variety of etiological factors. D-dimer (DD) is one of markers established in the etiological diagnosis of stroke. In this study, differential diagnosis of the subgroups of stroke and the relationship between the severity of stroke and the prognosis is investigated in association with the DD levels. Material and Metod: In this study, the patients who had a stroke and applied to the Clinic of Neurology at Şişli Etfal Education and Resarch Hospital in 24 hours has been included prospectively. All patients’ plasma D-dimer levels has been measured for two times firstly in 24 hours and the second between 8.-10. days. The etiological subgroups were determined according to TOAST criterias. The stroke severity has been evaluated in acute periode by National İnsitutes of Health Stroke Scale (NIHSS), the prognosis has been evaluated subsequent periode by Modifiye Rankin scala (mRS) and Barthell scala. Results: In this study 40 patients with stroke including 15 women and 20 healthy control patients including 12 women were included. In our study, the level of DD in ischemic stroke patients in the early period is found to be higher compared with the healthy controls(p=0,018 p=0,019). But DD levels are not significantly higher in the atrial fibrillation and cardioembolic stroke patients compared with the other groups (p=0,490 p=0,251 and p=0,333 p=0,519). When the relationship between the severity of the stroke and the prognosis is investigated, high DD levels are found to be associated with disabilities. Conclusion: DD is an applicable biomarker in the early period of ischemic stroke. Although there are many factors that affect the level of DD, DD levels may be an indicator of progressive stroke and can provide information about prognosis seems to be able to say. |
2. | Anesthesia experiences outside of the operating room Hacer Şebnem Türk, Ferda Aybey, Oya Ünsal, Mehmet Eren Açık, Naim Ediz, Sibel Oba doi: 10.5350/SEMB2013470102 Pages 5 - 10 Introduction And Aim: Thanks to technological developments, invasive and non-invasive diagnostic and therapeutic procedures have been done at the outside of the operating room. In this manner, to provide anesthesia at the outside of the operating room, anesthesia teams have been found. In this study, we aimed to report our anesthesia teams’ experiences. Materials And Methods: We reviewed the procedures that was experienced at outside the operating room from October 2010 to April 2012 retrospectively. 3583 Patients who required anesthesia at the outside of the operating room included the study, and their sexes, ages, ASA status, procedures, and anesthesia complications were recorded. Results: Patients’ sex ratio male/female 1671/1912; ranged in age from 20 day to 91 years; with the mean age 48,52±28,4. ASA status were, ASA I 1958, ASA II 1296, ASA III 318, ASA IV 11. Anesthesia procedures were for 1837 colonoscopy, 536 gastroscopy, 131 ERCP endoscopic retrograde cholangiopancreatography, 811 MRI magnetic resonance imaging, 62 CTI computerized tomography imaging, 234 ECT electroconvulsive therapy, 106 RT radiotherapy, 40 angiographic aneurysm embolization, 9 angiographic venous sampling, 43 carotis stent, and 63 other radiologic interventions. For sedation; 1960 Patient received propofol + alfentanil, 740 only propofol, 544 propofol + fentanyl, 115 ketofol, 65 midazolam+ketamin 83 dexmedetomidine. For electroconvulsive therapies, 90 patient received etomidate + succinyl choline, 144 propofol + succinyl choline. 40 patient received general anesthesia for embolisation procedures. There are no major complication occured except one patient experienced intracranial hemorrhage during colonoscopy. In minor complications; 12 patient experienced respiratory depression, 41 bradycardia, 144 oxygen desaturaion, 191 prolonged recovery from anesthesia, 8 vomiting. Conclusion: Anesthesia procedures at the outside of the operating room are frequently used in all medical interventions and at all ages. Remote locations from operating room, inadequate equipment and monitors,not enough space in the working environment, providing anesthesia outside the operating room is challenging and requires expertise and skill. The secret of success in anesthesia in remote locations is the skilled anesthesiologist with the appropriate equipment and drugs, along with adequate backup facilities. Anesthesia procedures at the outside of the operating room are guarding the patients safety and welfare, minimising physical discomfort and pain, providing physicians’ comfort. |
3. | Percutaneous tracheotomy practices in our intensive care unit (ICU) Tolga Totoz Cangül, Hacer Şebnem Türk, Pınar Sayın, Oya Ünsal, Surhan Çınar, Sibel Oba doi: 10.5350/SEMB2013470103 Pages 11 - 15 Introduction and Objective: Percutaneous tracheotomy practice is usually preferred at ICU for the advantages of able to be applied in a short time and at the bedside and it causes less bleeding. It is the alternative of surgical tracheotomy. The aim of this study is to analyze tracheotomies that were opened in our ICU in last 4 years, within the terms of practice day, practicing duration and post practice complications. Method: 132 percutaneous tracheotomy practiced cases of 603 cases that were treated in ourreanimation unit between 01.01.2007 and 31.12.2010 were analyzed. Percutaneous tracheotomy practices were conducted via Griggs technique by a team. Demographic information, practice day, total mechanical ventilation days, practicing duration and post practice complications were recorded. Findings: 603 cases were followed up and treated in ICU in last 4 years. 132 Percutaneous tracheotomy practices were applied in this period. It is figured out that women-man ratio was 62/70, the mean of age of the cases was 58.65±17.22 years, the mean hospitalization time of cases was 38.77±28.74 days, the mean intubation time before tracheotomy practice was 8.20±5.44 days, total mechanical ventilation days 26.85±21.70 and the mean practicing duration of operation was 6.1±2.1 minutes. 86 cases were deceased due to the comorbidities at ICU. 46 cases were transferred to the related services. Total complication (8 cases) were encountered. Result: Percutaneous tracheotomy which was practiced for indications such as need for mechanical ventilation for long time, easing weaning, providing urgent airway in ICU; is simple, has low complication ratio and is minimally invasive practice. |
4. | The causes of neonatal mortality in neonatal intensive care unit in 5 years (2007-2011) Selda Arslan, Ali Bülbül, Ayşe Şirin Aslan, Evrim Kıray Baş, Mesut Dursun, Sinan Uslu, Asiye Nuhoğlu doi: 10.5350/SEMB2013470104 Pages 16 - 20 Aim: This study was aimed to present the demographic information about neonates who were hospitalized and followed in our neonatal clinic and who died during follow-up. Material and Methods: In this study, records of neonates who died in our Neonatal Clinic in five years (from 1 January 2007 to 31 December 2011) were evaluated retrospectively. Neonatal mortality rates, perinatal-maternal risk factors and causes of mortality were determined. Results: During the five years, 5491 patients admitted in our clinic and 167 of them died. The mortality rate was 3,04%. The rate of neonates who died in the first 24 hours was 15,6%, whereas 74,9% of them died in the first 7 days of life. The gender distribution of infant deaths was found 46.8% female and 53.2% male. The rate of consanguineous marriage was 28,1%. The rate of mothers <19 years of age was 2,3%; whereas >35 years of age was 14,3%. The rate of neonates who were born <37 weeks of gestational age was 61.6%, whereas 29,9% of them were <28 weeks of gestational age; 37,1% of them were <1000 g of birth weight and 64,6% of them were <2500 g. The most common causes of neonatal mortality were determined as respiratory distress syndrome and prematurity (24.6%), neonatal sepsis (14.9%) and congenital anomalies (10.2%). Other causes were found perinatal asphyxia (8.9%), other respiratory problems (pneumothorax, meconium aspiration syndrome, congenital diaphragm hernia, etc.) (8.9%), cyanotic congenital heart disease (8.4%), metabolic diseases (7.7%), intraventricular hemorrhage (7.7%), necrotizing enterocolitis (3.6%) and others (4.9%). Conclusion: Prematurity and congenital anomalies are still frequent reasons of neonatal deaths. To establish preventable mortality reasons and prevent relevant conditions can be helpful to decrease neonatal mortality rates. |
5. | Arthroscopic rotator cuff repair Ibrahim Kaya, Akın Uğraş, Ahmet Ertürk, Erhan Bayram, Ibrahim Sungur, Samed Ordu, Murat Yılmaz, Ercan Çetinus doi: 10.5350/SEMB2013470105 Pages 21 - 24 Purpose: Clinical and functional arthroscopic repair results of rotator cuff tears which have been diagnosed both radiographically and clinicaly have been evaluated. Patients And Method: 26 patients treated with arthroscopic rotator cuff tear repair have been studied. Functional scores at the last follow-up were recorded. Mean age was 52.85±8.39 (range 38- 71), Mean follow up time was 36.6±16.6 (range 14-56). 10 patients were (38.5%) male and 16 (61.5%) were female. Preoperatively patients were examined radiologically with X ray and MR and clinically with constant score. Postoperative constant scores were recorded. Results: 18 (69.2%) of the effected shoulders were on the right side and 8 (30.2%) were on the left side. 3 (13.5%) of the patients went through acromioplasty. 76.9 % of the 26 patients had only supraspinatus tear where as in 23.1% of the patients concomitant infraspinatus tear was detected. Ethiologically three (11.5%) patients had history of shoulder trauma. Preoperative mean constant score was 52.89 (33-64) and postoperative mean constant score was 82±11.7 (56-100). All patients had significant increase in constant scores (p=0.000). Eight (30.7%) patients scored excellent, 10 (38.4%) patients good, seven (26.8%) patients fair and one (3.8%) patient bad. Conclusion: In selected cases, when the tear is not massive, arthroscopic rotator cuff repair may be the preferred treatment method becouse of its predictable good results and relatively less complication rate. Routine acromioplasty or subacromial decompression are not recommended. |
CASE REPORT | |
6. | Positive pathergy test association with sweet syndrome and acute myeloblastic leukemia Güldehan Atış, Ayşegül Ilhan, Berrin Karadağ, Sema Basat, Damlanur Sakız, Özlem Ton, Ilknur Kıvanç Altunay, Yüksel Altuntaş doi: 10.5350/SEMB2013470106 Pages 25 - 29 Sweet’s syndrome is a skin disease, which can be described as an acute febrile neutrophilic dermatosis with unknown etiology. SS can accompany infectious diseases and malignancies. Approximately 20 percent of patients with Sweet’s syndrome have an associated malignancy. Most commonly acute myelomonocytic leukemia, account for 85% percent of the associated malignancies. Pathergy test positivitiy can be detectable in patients with SS whereas pathergy test positivity is a rare condition patient with paraneoplastic SS. We report a 80-year old woman with positive pathergy test associated SS and AML. |
7. | Hidden danger in neck pain: Carotidynia Barış Türk, Feride Aydan Öztürk, Irfan Çelebi, Hacer Şebnem Türk doi: 10.5350/SEMB2013470107 Pages 30 - 34 Carotidynia is a neck pain syndrome, characterized by unilateral tenderness to palpation over the carotid bifurcation area. The differential diagnosis for carotidynia should be done carefully for the proper identification of this syndrome. The differential diagnosis for carotidynia includes large-vessel vasculitides such as Takayasu’s and temporal arteritis, arteriosclerosis, thrombosis, fibromuscular dysplasia, dissection and aneurysm, as well as other non-vascular diseases such as lymphoedemas, sialodenitis, thyroiditis, peritonsiller abse or neck neoplasms. Takayasu’s arteritis is a rare chronic systemic granulomatous inflammatory disease that affect the aorta and its major branchs with unknown etiology. Carotidynia may be a clinical sign of Takayasu arteritis and other large vessel vasculitides. In this study, we report ultrasonographic and magnetic resonance imaging findings in two patients with idiopatic carotidynia and Takayasu arteritis as a cause of carotidynia. |
8. | Giant ovarian masses, gynecologic, anestetic and pathologic assessment; analysis of four cases Alev Atış Aydın, Savaş Özdemir, Kaan Pakay, Ulufer Sivrikaya, Nedim Polat, Nimet Göker doi: 10.5350/SEMB2013470108 Pages 35 - 40 Ovarian masses sometimes can be seen as bulky masses reaching to huge amounts. Most pathologic signs can be attributed to compression effect on intraabdominal organs, vascular structures and ascites made by tumor. After removal of such huge pelvic masses, serious clinical hypotension and inferior vena cava (IVC) syndrome can be seen related to the aspiration of high levels of fluid or resection of bulky mass. Here, we present four cases of bulky ovarian masses by means of gynecologic surgery, anaesthesia and pathology. Case: 54, 35, 39, 42 years old patients having 20 kg and 40x20cm; 14 kg and 40x40x40 cm, 17 kg and 45x50 cm and 53x50 cm adnexal masses respectively were operated. Histopathologies were found each to be the first two borderline mucinous carcinomas, third one was benign endometrioid tumor and the fourth one was mucinous cystadenoma complexed with teratom structures. On preoperative assessment, patients had dyspnea and tachypnea due to huge abdominal distention, blood gas parameters were hypoxic. To prevent supin hypotensive syndrome and other complications peroperatively, cases were evaluated by anesthesiology and the appropriate anesthesia technique was chosen, no major complications were seen in the peroperative or postoperative periods. Discussion: Giant ovarian cyst excision may be associated with significant mortality. Most of the problems are due to the size of the cyst and to the patient‘s poor condition. Serious problems in this case mainly develop because of intraoperative blood loss and duration of the operation, postoperative hypotension and electrolyte disorders may be seen. Special attention should be paid to ventilator monitoring and hemodynamic assessment peroperatively and intraoperative fluid imbalance, hypotermia and coagulopathy regulation and the operative approach in the planning area needs to be done carefully. |
9. | A rare complication of totally implantable venous access device in a pediatric patient: a case report Sibel Oba, Meltem Aydoğmuş, Özgür Özbağrıaçık, Mehmet Eren Açık, Saliha Berber Pehlivan doi: 10.5350/SEMB2013470109 Pages 41 - 44 Implanted vascular access devices (ports catater) are widely used in pediatric haematology and oncology patients. They reduce the intravenous therapy difficulties and increase the quality of lives of oncologic patients. Complications are rare with experienced hands. Education of users, correct and frequent care, appropriate postoperatively use are important. Correct procedure and careful usage decrease the incidence of complications. We present a case where a perforation and leakage of ports catater occured due to improper usage. |
REVIEW ARTICLE | |
10. | Review of incision techniques in a case with frontozygomatic dermoid cyst Can Pamukcu, Serkan Erdenöz, Sabit Kimyon, Alper Mete, Gülcihan Açış doi: 10.5350/SEMB2013470110 Pages 45 - 48 Dermoid cysts are the most frequent periorbital tumors. The primary concern after total excision is an acceptable cosmetic result. Localization of incision during surgery effects the healing process and cosmetic result. In this report, we reviewed incision techniques while presenting a case in which we used upper skin crease incision for dermoid cyst excision. |