Med Bull Sisli Etfal Hosp. Kabul Yazýlar: SETB-60343 | DOI: 10.14744/SEMB.2023.60343

Demir Eksikliði Çocuklarda Ýnguinal Herni Geliþimi Ýçin Risk Faktörü Olabilir

Birsen Harma¹, Tuðba Raika Kýran², Feyza Ýnceoðlu^3
1Malatya Turgut Özal Üniversitesi, Çocuk Cerrahisi Anabilim Dalý, Pediatrik Yanýk Ünitesi, Malatya
²Malatya Turgut Özal Üniversitesi, Biyokimya Anabilim Dalý, Malatya
³Malatya Turgut Özal Üniversitesi, Týp Fakültesi, Biyoistatistik Anabilim Dalý, Malatya

Amaç:
Bu çalýþmada, inguinal herni tanýsý ile ameliyat edilen pediatrik hastalarýn rutin hemogram ve
biyokimyasal parametrelerinin etyopatogenez ile iliþkisi araþtýrýldý.
Gereç ve Yöntem
Ocak 2019-Kasým 2022 tarihleri arasýnda inguinal herni nedeniyle opera edilen seksen olgu
çalýþmaya dahil edildi. Hastane kayýtlarý kullanýlarak, bilinen herhangi bir hematolojik veya
metabolik hastalýk öyküsü veya düzenli ilaç kullanýmý olmayan seksen pediatrik hasta ile de bir
kontrol grubu oluþturuldu. Her iki grupta da hemoglobin (Hgb), hematokrit (Htc), ortalama
korpusküler hacim (MCV), ortalama korpusküler hemoglobin (MCH), ortalama korpusküler
hemoglobin konsantrasyonu (MCHC), eritrosit daðýlým geniþliði (RDW) ve trombosit (PLT)
deðerlerini karþýlaþtýrmak için istatistiksel analiz yapýldý.
Bulgular
Çocuk hastalarýn yaþ aralýðý 1-14 yýl idi. Seksen çocuðun 47'si (%58,8) erkek, 33'ü (%41,3)
kadýndý ve yaþ ortalamasý 5,79 ± 3,26 saptandý. Ýn guinal herni hastalarýnda Hgb, Htc, MCH,
MCHC ve MCV deðerleri kontrol grubundakilere göre istatistiksel olarak anlamlý derecede
düþük (p<0.05) ve RDW deðerleri ise anlamlý derecede yüksek bulundu (p<0.05).
Sonuç
Kontrol grubu ile karþýlaþtýrýldýðýnda, M CH, MCHC, MCV, Hgb, HTC deðerlerinde gözlenen
azalma ve hasta grubunda RDW'deki artýþ, demir eksikliðinin muhtemel etkisini
düþündürmektedir. Bu spesifik deðiþiklikler, demir eksikliðinin kollajen yapýsýnda yapýsal
deðiþikliklere yol açarak çocukluk çaðýndaki inguinal hernilerin etyopatogenezine katkýda
bulunabileceðini düþündürmektedir. (SETB-2023-01-013)

Anahtar Kelimeler: inguinal herni, çocuk, demir eksikliði, Eritrosit Daðýlým Geniþliði(RDW)

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Iron Deficiency May Be A Risk Factor For Inguinal Hernia Development In Children

Birsen Harma¹, Tuðba Raika Kýran², Feyza Ýnceoðlu^3
1Department of Pediatric Surgery, Pediatric Burn Unit, Malatya Turgut Özal University, Malatya, Türkiye
²Department of Biochemistry, Malatya Turgut Özal University, Malatya, Türkiye
³Department of Biostatistics, Faculty of Medicine, Malatya Turgut Ozal University, Malatya, Türkiye

Objective
This case control study aimed to investigate whether the routine hemogram and biochemical
parameters of pediatric patients who have undergone surgery for inguinal hernia are associated
with the etiopathogenesis of the disease.
Methods
Eighty cases of inguinal hernia surgery performed between January 2019 and November 2022
were included in the study. A control group was also established using hospital records,
consisting of eighty pediatric patients without any known history of hematological or metabolic
disease or use of regular medication. Statistical analysis was conducted to compare the total
hemoglobin (Hgb), hematocrit (Htc), mean corpuscular volume (MCV), mean corpuscular
hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), erythrocyte
distribution width (RDW) and thrombocyte (PLT) values in both groups.
Results
The age range of the pediatric patients was 1-14 years. Of the eighty children, 47 (58.8%) were
male and 33 (41.3%) were female, with a mean age of 5.79 ± 3.26. The values of Hgb, Htc,
MCH, MCHC, and MCV in the inguinal hernia patients were found to be statistically
significantly lower than those in the control group (p<0.05). Additionally, the patient RDW
values were found to be statistically significantly higher than those in the control group
(p<0.05).
Conclusion
Compared to the control group, the observed decrease in MCH, MCHC, MCV, Hgb, HTC
values, as well as the increase in RDW in patient group, suggests a predisposing effect of iron
deficiency. These specific changes suggested that iron deficiency may lead structural changes
in the collagen construction and may contribute the etiopathogenesis of childhood inguinal
hernia.

Keywords: inguinal hernia, child, iron deficiency, Erythrocyte Distribution Width (RDW)

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