Common skin findings in children with acute leukemia

Aim: Leukemias are the most common malignancies in childhood with a proportion of %25-40. Manifestations of the skin findings can be a router. There are only a few researches in the literature about this subject. Our aim was to determine the skin findings in children with acute leukemia.
Materials and Methods: The cases who were treated and followed up in Pediatric Hematology and Oncology Clinics were included in the study. The diagnose and duration of the disease, whether in remission or not and patients’ treatment were noted. Dermatologic examination was recorded as a standard form.
Results: 59 acute leukemia patients (32 boys, 27 girls; aged 18 months to 17 years - mean: 8.69 years) were included in the study. 6 of the patients were acute myeloblastic leukemia and 53 of them were acute lymphoblastic leukemia. Patients were seen 1-6 times (mean: 2.30) and disease periods were 1 month to 8 years (mean: 2.31 years). 89.8% of the patients were in remission (53/59: 31 boys, 22 girls). In the cases of 93.2%, skin lesions were observed at least one examination (except 1 acute myeloblastic leukemia and 3 acute lymphoblastic leukemia patients). Skin infiltration of acute leukemia was not found. Kserosis, diffuse alopecia, miliaria, purpura and pitriasis simplex were the most frequent dermatoses.
Conclusions: 93.2% of the patients were observed to have skin lesions. Nonspesific skin lesions were detected in the foreground. Although these results are compatible

Akut lösemili çocuklarda sýk görülen deri bulgularý

Amaç: Lösemiler, %25-40 gibi bir oranla çocukluk çaðýnýn en sýk görülen malinitesidir. Deri bulgularý hastalýðýn seyri sýrasýnda yönlendirici nitelik taþýyabilmektedir. Literatürlerde bunu konu alan az sayýda çalýþma bulunmaktadýr. Bu çalýþma ile amacýmýz akut lösemili çocuk hastalarda gözlenen deri bulgularýný saptamaktý.
Gereç ve Yöntemler: Hastanemiz Pediatrik Hematoloji ve Onkoloji Kliniði’inde takip ve tedavi edilen olgular çalýþmaya alýndý. Olgularýn hastalýðý, süresi, remisyonda olup olmadýðý ve tedavisi not edildi. Dermatolojik muayenesi yapýlarak standart forma kaydedildi.
Bulgular: Yaþlarý 18 ay-17 (ort: 8.69) arasýnda deðiþen 59 akut lösemi hastasý (32 erkek, 27 kýz) çalýþmaya alýndý. Hastalarýn 6‘sý akut myeloblastik lösemi, 53‘ü akut lenfoblastik lösemi idi. Hastalar 1-6 kez (ort: 2.30 kez) görüldü. Hastalýk süreleri 1 ay-8 yýl (ort: 2.31 yýl) arasýnda deðiþmekteydi. Hastalarýn %89.8‘i (53/59: 31 erkek, 22 kýz) remisyondaydý. Olgularýn takiplerinde %93.2’sinin (1 akut myeloblastik lösemi ve 3 akut lenfoblastik lösemi olgusu hariç) en az bir muayenesinde deri lezyonu gözlendi. Akut lösemilerin deri infiltrasyonuna dair bulguya rastlanmadý. Kserosis, diffüz alopesi, miliarya, purpura ve pitriasis simpleks en sýk gözlenen beþ dermatozdu.
Sonuç: Olgularýmýzda %93.2 oranýnda deri lezyonu gözledik. Nonspesifik deri lezyonlarýný ön planda saptadýk. Bu sonuç benzer yayýnlarla uyumlu olmakla beraber; geniþ serilerle yapýlan çalýþmalarla daha saðlýklý sonuçlar elde edileceðini düþünmekteyiz.