Radiologic findings in a case of hypothalamic hamartoma

Hypothalamic hamartoma, also called tuber cinereum hamartoma is a rarely seen lesion located between the infundibular stalk anteriorly and the mamillary bodies posteriorly. These lesions are few milimeters to I -2 centimetres in size and composed of nonneoplastic heterotopic normal neuronal tissue. Clinically two distinc presentations have been noted, accompanied with precocious puberty or seizure. Since the diagnosis depends on the radiologic demonstration of the lesion in the presence of appropriate clinical setting, an appropriate imaging technique should be used, with detailed examination for small sized lesions. Biopsy is not an option mostly even for lesions with a larger size because of central location and this shows the importance of radiologic imaging and differential diagnosis. In this report we discussed the radiologic imaging features of hypothalamic hamartoma detected in 9 months old male patent.

Hipotalamik hamartom’lu olguda radyolojik bulgular

Tuber cinereum hamartomu olarak da adlandýrýlan hipotalamik hamartomlar nadir görülen, infundibüler stalk ile mamiller cisimcik arasýnda kalan hipotalamik bölgede lokalize, milimetrik boyutlardan birkaç santimetreye kadar boyutlarda olabilen, neoplastik olmayan heterotopik normal nöronal dokudan oluþan kitlelerdir. Klinik olarak prekok puherte veya epilepsi ile ortaya çýkan iki farklý tipi mevcuttur. Uygun klinik bulgularýn varlýðýnda taný radyolojik olarak milimetrik boyutlarda olsa hile lezyonun radyolojik olarak görüntülenmesine baðlýdýr. Büyük boyutlu lezyonlarda bile lokalizasyon nedeniyle biopsinin zor olmasý ayýrýcý tam açýsýndan radyolojik görüntülemenin önemini ortaya koymaktadýr. Bu olgumuzda 9 aylýk erkek çocukta saptadýðýmýz biiyük boyutlu hipotalamik hamartom olgusu eþliðinde hipotalamik hamartomun görüntüleme bulgularýný tartýþtýk.