Primary prostat lymphoma (case presentation)

Objective: Lymphoma of prostate is an uncommon disease. We report a case of prostate lymphoma.
Methods/Results: A 60 year-old male patient was referred to the Urology department with a clinical picture of prostatism. Biopsy was performed, and pathology revealed a primary prostate lymphoma. The patient was referred to Radiation Oncology Clinic. He received 6 cycle CHOP chemotherapy and external pelvic radiotherapy. I year later inguinal lymph node metastases was detected. He received 6 cycle second line VEBEP chemotherapy. The patient is currently followed by regular visits to Radiation Oncology Clinic.
Conclusions: Of the cases reviewed, mean age at diagnosis was 57 years. Clinical behavior was with prostate symptoms, with or without acute urinary symptoms and sometimes manifestations of renal failure due to obstructive uropathy, as well as general symptoms (astenia, anorexia, weight loss). PSA values remain unaltered in prostate lymphoma patients. Histologic diagnosis may be made by transrectal prostate biopsy Ultrasound and CT scan are of great utility for diagnosis of both local and distant tumors. From a therapeutic point of view, surgery for the obstruction of the lower urinary tract (TUR or retropubic prostatectomy) may be necessary, as well as the chemotherapy and radiotherapy.

Primer prostat lenfomasý olgu sunumu

Amaç: Prostat lenfomasý nadir görülen malign hastalýktýr.
Metod/Sonuçlar: 60 yaþýnda erkek hasta prostatizm semptomlarý ile üroloji kliniðine müracaat etmiþti. TUR- biopsi sonucu primer prostat lenfoma tanýsý konuldu. Radyasyon Onkolojisi Kliniðine yönlendirilen hastaya 6 kür CHOP kemoterapisi ardýndan eksternal Radyoterapi primer bögeye uygulandý. 1 yýl sonra inguinal lenf nodu metastazý saptandý. Ve kür 2. seri kemoterapi olarak VEBEP rejimi uygulandý. Hasta halen kliniðimizde takip edilmektedir.
Tartýþma: Primer prostat lenfoma görülme yaþý literatürde 57 olarak bildirilmiþtir. Klinik olarak; prostatizm semptomlarý, renal yetmezlik bulgularý, obstrüktif üropati, astenia, kilo kaybý, anoreksi görülebilir. PSA düzeyinintaný ve takipte önemi yoktur. Histolojik taný prostat biopsisi ile konulmaktadýr. Ultrasonografý ve CT taný ve takipte çok önemlidir. Tedavide, TUR veya retropubik prostatektomi sonrasý, kemoterapi ve radyoterapi kullanýlýr.