Obesity, Hypertrichosis and Sex Steroids: Are these Factors Related to the Pilonidal Sinus Disease?

Objectives: Pilonidal sinus disease causes chronic inflammation of the skin and subcutaneous fatty tissue, and it commonly localises in the sacrococcygeal region. This study evaluated the effects of hypertrichosis, family history, obesity and sex steroids in 298 patients with pilonidal sinus disease.
Methods: The medical records of 618 patients treated at the General Surgery Clinic of Malatya State Hospital for primary pilonidal sinus disease between January 2014 and December 2017 were evaluated retrospectively.
Results: Female sex and family histories of pilonidal sinus disease and hypertrichosis were significantly higher in patients with than without hypertrichosis (p=0.030, p=0.035, p<0.001). The mean progesterone level was significantly lower in female patients with hypertrichosis than female patients without hypertrichosis (p=0.003).
Conclusion: Being overweight or obese, having an occupation that requires long-time sitting and having a family history predisposed to developing pilonidal sinus disease.

Obesity, Hypertrichosis and Sex Steroids: Are these Factors Related to the Pilonidal Sinus Disease?

Amaç: Pilonidal sinüs hastalýðý genellikle sakrokoksigeal bölge yerleþen ve ciltte - deri altý yað dokusunda kronik enflamasyon ile ilerleyen bir hastalýktýr. Bu çalýþmada pilonidal sinüs hastalýðý olan 298 hastanýn hipertrikozu, aile öyküsü, obezite ve seks steroidlerinin etkileri deðerlendirildi.
Yöntem: Malatya Devlet Hastanesi Genel Cerrahi Kliniðinde Ocak 2014 - Aralýk 2017 tarihleri arasýnda primer pilonidal sinus hastalýðý nedeniyle tedavi edilen 618 hastanýn týbbi kayýtlarý retrospektif olarak deðerlendirildi.
Bulgular: Kadýn cinsiyet ve aile öyküsü pilonidal sinüs hastalýðý ve hipertrikoz, hipertrikozu olmayan hastalardan anlamlý olarak yüksekti (p = 0.030, p = 0.035, p <0.001). Hipertrikozlu kadýn hastalarda, ortalama progesteron düzeyi hipertrikoz olmayan kadýnlardan anlamlý olarak düþüktü (p = 0.003).
Sonuç: Aþýrý kilolu veya obez olmak, uzun süre oturmayý gerektiren bir mesleðe sahip olmak ve pilonidal sinüs hastalýðýnýn geliþmesine yatkýn bir aile öyküsü olmasý.