Primary renal small cell carcinoma: case report

Renal small cell carcinoma is a highly aggressive malignant tumor that has the potential of distant metastasis and it shows neuroendocrine and epithelial neoplasm features which are ultrastructural and immunohistochemical. Approximately 5% of small cell carcinomas are localized in extrapulmonary and renal localization is rarely seen. Although nephrectomy and chemotherapy are recommended for treatment, life expectancies are quite short. A 75-year-old woman, who had a primary small cell carcinoma of the right renal pelvis, was the subject of our case. Nephrectomy was performed on the patient and small cell carcinoma -containing areas of high grade transitional epithelium cell was reported after pathological evaluation. The patient, who had liver metastasis and thus received 5 cures of chemotheraphy (cisplatinum, etoposide), died 20 months after the diagnosis.

Primer böbrek kaynaklý küçük hücreli karsinom: Olgu sunumu

Renal küçük hücreli karsinom, ultrastrüktürel ve immunohistokimyasal olarak nöroendokrin ve epitelyal neoplazm karakteristikleri gösteren oldukça agresif ve uzak metastaz potansiyeli taþýyan, nadir bir malign tümördür. Küçük hücreli karsinomlarýn yaklaþýk %5’i ekstrapulmoner yerleþimlidir ve böbrek yerleþimine de oldukça az rastlanmaktadýr. Tedavi olarak, nefrektomi ve sonrasýnda kemoterapi önerilse de yaþam süreleri oldukça kýsadýr. Vakamýz, 75 yaþýnda, sað renal pelvis yerleþimli, primer renal küçük hücreli karsinomu olan bir kadýn hastaydý. Hastaya nefrektomi gerçekleþtirildi ve patolojik deðerlendirme sonrasý, yüksek dereceli deðiþici epitel hücreli karsinom alanlarý da içeren küçük hücreli karsinom olarak rapor edildi. Kontrollerinde karaciðer metastazý saptanan ve 5 kür kemoterapi (sisplatin, etoposid) uygulanan hasta, taný konulduktan 20 ay sonra yaþamýný kaybetti.