Evaluation of the Design and Methodology of Applications to the Local Ethics Committee

Altuntas, Yuksel; Yildirmak, Zeynep Yildiz; Erdogan, Sarper; Seckin, Deniz; Aksu Cerman, Asli; Yapislar, Hande; Onal, Gulsum; Elcioglu, Kubra; Eren, Nezaket; Necioglu Orken, Dilek

Volume : 58 Issue : 4 Year : 2024

58/4Current Issue Accepted Articles Archive Covers Most Accessed Articles

Author Contribution Form

ICMJE COI Form

Evaluation of the Design and Methodology of Applications to the Local Ethics Committee [Med Bull Sisli Etfal Hosp]

Med Bull Sisli Etfal Hosp. 2021; 55(4): 450-456 | DOI: 10.14744/SEMB.2021.47542

Evaluation of the Design and Methodology of Applications to the Local Ethics Committee

Yuksel Altuntas¹, Zeynep Yildiz Yildirmak², Sarper Erdogan³, Deniz Seckin³, Asli Aksu Cerman⁴, Hande Yapislar⁵, Gulsum Onal⁶, Kubra Elcioglu⁷, Nezaket Eren⁸, Dilek Necioglu Orken⁹
¹Department of Endocrinology Metabolism, University of Health Sciences Turkey, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey
²Department of Pediatric Hematology and Oncology, University of Health Sciences Turkey, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey
³Department of Public Health, �stanbul University-Cerrahpa�a, Cerrahpa�a Faculty of Medicine, Istanbul, Turkey
⁴Department of Dermatology, University of Health Sciences Turkey, Sisli Hamidiye Etfal Training and Research Hospital, Istanbul, Turkey
⁵Department of Physiology, Acibadem Mehmet Ali Aydinlar University, Faculty of Medicine, Istanbul, Turkey
⁶Department of Medical History and Ethics, Trakya University, Faculty of Medicine, Edirne, Turkey
⁷Department of Pharmacology, Marmara University Recep Tayyip Erdo�an Complex, Faculty of Pharmacy, Istanbul, Turkey
⁸Department of Biochemistry, �stanbul Yeni Y�zy�l University, Faculty of Medicine, Istanbul, Turkey
⁹Department of Neurology, Memorial Hospital, Istanbul, Turkey

Objectives: Proposals for scientific studies must have an original hypothesis and the appropriate design and methodology to test the premise.
Methods: This study is an evaluation of the suitability of applications submitted to a local ethics committee (EC) and the rate of publication of that research.
Results: A total of 899 files submitted for EC approval were retrospectively assessed. The EC found that the description of the methods in 44% of the applications was inaccurate, and that this type of error was most often seen in submissions from the surgical branch. In all, 52% of the applications for which we were informed about their final status were not published.
Conclusion: The results suggest that improved training in epidemiology is required to reduce the number of application errors and that new regulations could help to motivate healthcare personnel to conduct scientific research and publish their findings.

Keywords: Case-control study, epidemiology; ethics committees; interventional studies; research misconduct; thesis studies.

Evaluation of the Design and Methodology of Applications to the Local Ethics Committee

Yuksel Altuntas¹, Zeynep Yildiz Yildirmak², Sarper Erdogan³, Deniz Seckin³, Asli Aksu Cerman⁴, Hande Yapislar⁵, Gulsum Onal⁶, Kubra Elcioglu⁷, Nezaket Eren⁸, Dilek Necioglu Orken⁹
¹Sa�l�k Bilimleri �niversitesi T�rkiye, �i�li Hamidiye Etfal E�itim ve Ara�t�rma Hastanesi, Endokrinoloji Metabolizma Anabilim Dal�, �stanbul,
²Sa�l�k Bilimleri �niversitesi T�rkiye, �i�li Hamidiye Etfal E�itim ve Ara�t�rma Hastanesi, �ocuk Hematoloji ve Onkoloji Anabilim Dal�, �stanbul
³�stanbul �niversitesi-Cerrahpa�a, Cerrahpa�a T�p Fak�ltesi, Halk Sa�l�� Anabilim Dal�, �stanbul
⁴Sa�l�k Bilimleri �niversitesi T�rkiye, �i�li Hamidiye Etfal E�itim ve Ara�t�rma Hastanesi, Dermatoloji Anabilim Dal�, �stanbul
⁵Ac�badem Mehmet Ali Ayd�nlar �niversitesi, T�p Fak�ltesi, Fizyoloji Anabilim Dal�, �stanbul
⁶Trakya �niversitesi T�p Fak�ltesi T�p Tarihi ve Etik Anabilim Dal�, Edirne
⁷Marmara �niversitesi Recep Tayyip Erdo�an K�lliyesi, Eczac�l�k Fak�ltesi, Farmakoloji Anabilim Dal�, �stanbul
⁸�stanbul Yeni Y�zy�l �niversitesi T�p Fak�ltesi Biyokimya Anabilim Dal�, �stanbul
⁹Memorial Hastanesi, N�roloji B�l�m�, �stanbul

Ama�: Bilimsel �al��malara y�nelik yap�lan tasar�lar, orjinal bir hipoteze ve �neriyi test etmek i�in uygun tasar�ma ve metodolojiye sahip olmal�d�r.
Y�ntem: Bu �al��mada, yerel bir etik komiteye (EK) yap�lan ba�vurular�n uygunlu�u ve bu ara�t�rmalar�n yay�nlanma oran� de�erlendirilmi�tir.
Bulgular: Etik kurula onay� i�in ba�vurulan toplam 899 dosya retrospektif olarak incelendi. EK, ba�vurular�n %44'�nde metod tan�mlamalar�n�n hatal� oldu�unu ve bu t�r hatalar�n en s�k cerrahi bran�lar taraf�ndan yap�lan ba�vurularda g�r�ld��n� tespit etti. Toplamda, son durumu hakk�nda bilgilendirildi�imiz ba�vurular�n %52�si yay�nlanmad�.
Sonu�: Sonu�lar; epidemiyolojide iyile�tirilmi� e�itimin, ba�vuru hatalar�n�n say�s�n� azaltmak i�in gerekli oldu�unu ve yeni d�zenlemelerin sa�l�k personelini bilimsel ara�t�rma yapmaya ve bulgular�n� yay�nlamaya motive etmeye yard�mc� olabilece�ini g�stermektedir. (SETB-2021-09-280)

Anahtar Kelimeler: Vaka control �al��mas�, Epidemiyoloji, Etik Komiteler, Giri�imsel �al��malar, Ara�t�rma Hilesi, Tez �al��malar�

Corresponding Author: Asli Aksu Cerman
Manuscript Language: English

CITE

English Full Text Download citation RIS EndNote BibTex Medlars Procite Reference Manager Similar articles PubMed Google Scholar