Henoch-schonlein purpura in childhood: Clinical experience

Objective: Henoch-Schonlein purpura (HSP) is a common leukocytoclastic vasculitis of childhood characterized by purpuric skin lesions, arthritis, gastrointestinal and renal involvement, Our aim was to evaluate the clinical findings of our patients with HSP.
Study Design: 75 patients diagnosed as HSP who were hospitalized in our clinic between January 2002 and April 2005 were retrospectively evaluated.
Results: Mean age of the patients (55% boys and 45% girls) were 9.3 ± 3.1. Hospitalization rates were lowest during summer seasons. All patients had palpable purpura, 78% had GIS findings, 72% had arthritis or arthralgia and 33% had renal involvement. Occult blood was present in 49%, 6.7% had acute abdominal symptoms, scalp edema was present in 5.3% and scrotal edema in 12%. Mean follow-up period for patients with renal involvement was 22.3 ± 15 months. Renal biopsy was performed in 13 patients with serios renal involvement.
Conclusion: Although the most common finding in PISP is the purpura; arthritis, renal or gastrointestinal findings may be present previously or during the, follow-up. Other, causes of vasculitis should also be included in the differential diagnosis.

Henoch-schönlein purpuralý olgularýmýzýn deðerlendirilmesi

Amaç: Henoch-Schönlein Purpurasý (I1SP), çocukluk çaðýnda sýk görülen lökositoklastik bir vaskülittir. Sýklýkla palpabl purpura, artralji-artrit, gastrointestinal ve renal bulgular ile karakterize sistemik bir hastalýktýr. Bu çalýþmada HSP‘li hastalarýmýzýn klinik özelliklerinin deðerlendirilmesi amaçlandý.
Yöntem: Ocak 2002 - Nisan 2005 tarihleri arasýnda I. Çocuk Kliniðinde MSP tanýsý alarak yatýrýlan 75 hastanýn dosyalarý retrospektif olarak Ýncelendi.
Bulgular: Olgularýn yaþ ortalamasý 9.3 ± 3.1 yýldý. Hastalarýmýzýn %55’i erkek, %45‘i kýz idi. Yaz aylarýnda baþvuru oldukça nadirdi. Hastalarýn tamamýnda palpabl purpura, %78’inde GÝS tutulumu, %72’sinde artrit ya da artralji, %33’ünde renal tutulum mevcuttu. %49 hastada dýþkýda gizli kan pozitifliði vardý. Akut batýn tablosunda baþvuran %6.7 hasta mevcuttu. Saçlý deride ödem %5.3 hastada, skrotal ödem %I2 hastada saptandý. Böbrek tutulumu olan hastalarda ortalama izlem süresi-,22.-3 ± 15 aydý. Aðýr böbrek tutulumu olan toplam 13 hastaya böbrek biyopsisi yapýldý. Yorum: HSP’ nm en sýk görülen bulgusu cilt döküntüsü olmakla beraber, daha önce veya takipte eklem tutulumu, renal ve gastrointestinal bulgularýn ortaya çýkabileceði, diðer vas- kiilit tablolarýna eþlik edebileceði akýlda tutulmalý ve ayýrýcý tanýda dikkatli olunmalýdýr.