Med Bull Sisli Etfal Hosp. 2021; 55(1): 42-48 | DOI: 10.14744/SEMB.2020.33349

Discussion of Histopathological Findings of 954 Breast Reduction Specimens

Soysal Bas¹, Ali Can Aydin¹, Cagatay Oner¹, Ramazan Ucak², Selami Serhat Sirvan¹, Semra Karsidag^1
1Department of Plastic, Reconstructive and Aesthetic Surgery, University of Health Sciences Turkey, Sisli Hamidiye Etfal Teaching and Research Hospital, Istanbul, Turkey
²Department of Pathology, University of Health Sciences Turkey, Sisli Hamidiye Etfal Teaching and Research Hospital, Istanbul, Turkey

Objectives: Breast reduction is a frequently sought procedure by patients and one of the most commonly performed operations by plastic surgeons. Follow-up of histopathological results after reduction mammoplasty is very important. This study aimed to evaluate the histopathological results of patients undergoing bilateral reduction mammoplasty to determine the incidence of breast lesions and risk factors of high-risk breast lesions.
Methods: 477 patients who underwent reduction mammoplasty in the plastic surgery department between October 2013 and January 2020 were included in this study. Patients were evaluated according to age, body mass index (BMI), comorbidity factors, tobacco use, family history and histopathological findings.
Results: The mean age of patients was 42.43±12.05 years. Body mass index ranged from 23 to 34.6. As for comorbidity factors, 12 patients had hypertension, five patients had asthma and six patients had diabetes mellitus. Seventeen patients (3.6%) were smokers, and 25 (5.2%) patients had a family history of breast cancer. Among the patients, 2.3% were 20 years and under, 17.1% were between 21 and 30 years old, 21.5% were between 31 and 40 years old, 33.1% were between 41 and 50 years old, 18.2% were between 51 and 60 years old, and 7.5% were 60 years and above. 85.4% of histopathological findings consisted of normal breast tissue and nonproliferative breast lesion breast lesions. The incidences of proliferative breast lesions, atypical hyperplasia and in situ lesions were calculated as 5.7%, 2% and 0.4%, respectively. The mean follow-up period was 3.8±1.6 years.
Conclusion: Although preoperative breast cancer screening methods are used before the reduction mammoplasty, high-risk lesions may be encountered afterwards. One of the biggest advantages of reduction mammoplasty in addition to psychophysiological recovery is breast cancer risk reduction.

Keywords: Breast reduction, histopathologic result; nonproliferative breast lesion; proliferative breast lesion.

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954 Meme Küçültme Spesmeninin Histopatolojik Bulgularýnýn Tartýþýlmasý

Soysal Bas¹, Ali Can Aydin¹, Cagatay Oner¹, Ramazan Ucak², Selami Serhat Sirvan¹, Semra Karsidag^1
1Saðlýk Bilimleri Üniversitesi Türkiye Þiþli Hamidiye Etfal Eðitim ve Araþtýrma Hastanesi, Plastik, Rekonstrüktif ve Estetik Cerrahi Anabilim Dalý, Ýstanbul
²Saðlýk Bilimleri Üniversitesi, Þiþli Hamidiye Etfal Eðitim ve Araþtýrma Hastanesi, Patoloji Anabilim Dalý, Ýstanbul

Amaç: Meme küçültme, hastalar tarafýndan sýk baþvurulan bir prosedürdür ve plastik cerrahlar tarafýndan sýk yapýlan ameliyatlardan biridir. Redüksiyon mamoplasti sonrasý histopatolojik sonuçlarýn takibi çok önemlidir. Bu çalýþma, bilateral redüksiyon mamoplastisi uygulanan hastalarýn histopatolojik sonuçlarýný deðerlendirmeyi, meme lezyonlarýnýn insidansýný ve yüksek riskli meme lezyonlarýnýn risk faktörlerini belirlemeyi amaçlamýþtýr.
Gereç ve Yöntemler: Ekim 2013 - Ocak 2020 arasýnda plastik cerrahi bölümünde redüksiyon mamoplastisi uygulanan 477 hasta çalýþmaya dahil edildi. Hastalar yaþ, vücut kitle indeksi, komorbidite faktörleri, sigara kullanýmý, aile hikayesi ve histopatolojik bulgulara göre deðerlendirildi.
Bulgular: Hastalarýn yaþý ortalama 42.43 ± 12.05’idi. Vücut kitle indeksi 23-34.6 arasýnda deðiþmekte idi. Eþlik eden faktörler, 12 hastada hipertansiyon, 5 hastada astým ve 6 hastada diyabetes mellitus vardý. 17 hastada (% 3.6) sigara ve 25 (% 5.2) hastada meme kanseri öyküsü mevcuttu. Hastalarýn% 2.3'ü 20 yaþ ve altý, % 17.1'i 21 ila 30 yaþlarý arasýnda, % 21.5'i 31 ila 40 yaþlarý arasýnda,% 33.1'i 41 ila 50 yaþlarý arasýnda,% 18.2'si 51 ila 60 yaþlarý arasýndaydý. 7.5'i 60 yaþ ve üstünde idi. Histopatolojik bulgularýn% 85.4'ü normal meme dokusu ve nonproliferatif meme lezyonlarýndan oluþuyordu. Proliferatif meme lezyonlarý, atipik hiperplazi ve in situ lezyonlarýn insidansý sýrasýyla % 5.7, % 2 ve % 0.4 olarak hesaplandý. Ortalama takip süresi 3.8 ± 1.6 yýl idi.
Sonuç: Preoperatif meme kanseri tarama yöntemleri redüksiyon mamoplastisinden önce kullanýlsa da, yüksek riskli lezyonlarla karþýlaþýlabilir. Psikofizyolojik iyileþmeye ek olarak redüksiyon mamoplastisinin en büyük avantajlarýndan biri de meme kanseri riskinin azaltýlmasýdýr. (SETB-2020-04-041)

Anahtar Kelimeler: Meme küçültme, histopatolojik sonuç, proliferatif meme lezyonu, nonproliferatif meme lezyonu.

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