Med Bull Sisli Etfal Hosp. 2020; 54(2): 206-210 | DOI: 10.14744/SEMB.2020.02703

European Standard Series Patch Test Results in Contact Dermatitis Patients in a Tertiary Care Hospital

Ersoy Acer, Hilal Kaya Erdogan, Tayfun Batan, Zeynep Nurhan Saracoglu
Department of Dermatology, Eskisehir Osmangazi University Faculty of Medicine, Eskisehir, Turkey

Objectives: Sensitization of allergens varies among societies and also it is influenced by various factors, such as age and gender. It may even change over the years. In this study, we aimed to evaluate the patch test results in patients with contact dermatitis (CD) in our center.
Methods: European standard series patch test results of patients with CD between 2017 and 2018 were evaluated retrospectively.
Results: Of the 135 patients, 65 (48.1%) were males, 70 (51.9%) were females. The mean age of patients was 41.43±14.26 (11-78) years. In 78 (57.8%) patients, a positive reaction against at least one allergen was detected. The most common allergens were nickel sulfate (27.4%), potassium dichromate (14.8%), cobalt chloride (11.9%), textile dye mix (8.1%), fragrance mix i, ii (6.7%) and balsam of Peru (4.4%). The sensitization of nickel sulfate was higher in females and sensitization of cobalt chloride and potassium dichromate in males (p=0.03, 0.05, 0.03, respectively). In the multivariate logistic regression analysis, age was independently related to a positive reaction against at least one allergen.
Conclusion: Nickel sulfate, potassium dichromate, cobalt chloride and textile dye mix were the most common allergens. Legal regulations should be made to decrease exposure to allergens.

Keywords: Contact dermatitis, European standard series; nickel sulfate; patch test; potassium dichromate; textile dye mix.

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Üçüncü basamak bir hastanede kontakt dermatit hastalarýnda Avrupa standart seri yama testi sonuçlarý

Ersoy Acer, Hilal Kaya Erdogan, Tayfun Batan, Zeynep Nurhan Saracoglu
Eskiþehir Osmangazi Üniversitesi Týp Fakültesi, Dermatoloji Anabilim Dalý, Eskiþehir

Amaç: Alerjenlere duyarlanma toplumlar arasýnda farklýlýk gösterir, ayrýca yaþ ve cinsiyet gibi çeþitli faktörlerden etkilenir, yýllar içinde bile deðiþebilir. Bu çalýþmada merkezimizde, kontakt dermatitli (KD) hastalarda yapýlan yama testi sonuçlarýný deðerlendirmeyi amaçladýk.
Yöntem: Ýki bin on yedi-2018 yýllarý arasýnda KD’li hastalarýn Avrupa standart seri yama testi sonuçlarý retrospektif olarak deðerlendirildi.
Bulgular: Yüz otuz beþ hastanýn 65'i (%48,1) erkek, 70'i (%51,9) kadýndý. Hastalarýn yaþ ortalamasý 41,43 ± 14,26 (11-78) idi. 78'inde (%57,8) en az bir alerjene karþý pozitif reaksiyon tespit edildi. En sýk alerjenler nikel sülfat (%27,4), potasyum dikromat (%14,8), kobalt klorür (%11,9), tekstil boya karýþýmý (%8,1), koku karýþýmý Ⅰ, Ⅱ (%6,7) ve peru balsamý (%4,4) idi. Kadýnlarda nikel sülfat, erkeklerde kobalt klorür ve potasyum dikromat duyarlýlýðý daha yüksekti (sýrasýyla, p = 0.03, 0.05, 0.03). Çok deðiþkenli lojistik regresyon analizinde; yaþ, en az bir alerjene karþý pozitif reaksiyon ile baðýmsýz olarak iliþkiliydi.
Sonuç: Nikel sülfat, potasyum dikromat, kobalt klorür ve tekstil boya karýþýmý en sýk saptanan alerjenlerdi. Bu alerjenlere maruziyeti azaltmak için yasal düzenlemeler yapýlmalýdýr. (SETB-2019-08-114)

Anahtar Kelimeler: Avrupa standart seri, kontakt dermatit, nikel sülfat, potasyum dikromat, tekstil boya karýþýmý, yama testi

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