Pamidronate treatment in patient developed hypercalcemia due to hypervitaminosis D

Vitamin D supplementation in childhood in order to rickets prophylaxis is given from the neonatal period. However, inappropriate vitamin D supplementation may be administered by families for children’s growth and development and early teething or may be given high dose vitamin D for the treatment by physicians due to incorrect assessment of rickets laboratory findings. For these reasons, vitamin D intoxication related hypercalcemia in some cases determined. This article are presented for emphasize the efficacy of pamidronate treatment in vitamin D intoxication developed five month old girl after use of vitamin D once ampoules, developing hypercalcemia and nephrocalcinosis stage 2.

Yüksek doz d vitamini alýmý sonucu hiperkalsemi geliþen olguda pamidronat tedavisi

Vitamin D takviyesi, çocukluk çaðýnda rikets profilaksisi amacýyla yenidoðan döneminden itibaren verilmektedir. Bununla birlikte, aileler tarafýndan çocuklarýnýn büyüme ve geliþmesi, erken diþ çýkarmasý ya da vitamin takviyesi nedeniyle veya hekimler tarafýndan rikets laboratuvar bulgularýnýn iyi deðerlendirilmeden tedavi amaçlý olarak yüksek doz D vitamini verilmesi sonucunda D vitamini intoksikasyonlarý ve buna baðlý hiperkalsemi olgularý saptanmaktadýr. Bu yazýda, bir kez D vitamini ampül kullanýmý sonrasý hiperkalsemi ve evre 2 nefrokalsinozis geliþen beþ aylýk kýz olgu, tedavide pamidronat kullanýmýnýn etkinliðinin vurgulanmasý amacýyla sunulmuþtur.