MRI Findings of Patients with Partial Epilepsy

OBJECTIVE: In this study we have investigated the role of magnetic resonance imaging (MRI) in determining the etiology in 63 patients with partial epilepsy.
MATERIALS AND METJIODS: The MRI findings of 63 patients with partial epilepsy followed by Epilepsy Outpatient Department of Şişli Etfal Hospital Neurology Clinic were investigated retrospectively. The type of seizure was detemýined by the informatiorý taken from the patients and their relatives who had seen the seizure. The electroecephalogram was recorded twice yearly in each patient. All patients were screened in T1, T2 and proton density.
RESULTS: Thirty-two patients were female and 31 were male. The seizure type was simpily partial in 6 patients, complex partial in 14 patients and secondarily generalised in 43. EEG was pathologic in 47 patients and normal in 16. Thirty-six of 63 patients had abnormal MRI. Ten patients had atrophy, followed by 5 multiple, small lesion in white matter, 4 space occupying leisons. 4 developmental abnormalities, 3 hypoxic encephalopaty, 2 mesial temporal sclerosis, 2 venturicular asymmetry, 2 calcified lesion. 1 hydrocephaly, 1 vascular lesion, 1 multipl hamartomatous lesions in white matter in accordance with neurofibromatosis. One patient with hyperintense symmetrical lesions in occipital lobe could not he classified.
CONCLUSION: We claim that MRI is a very important tool revealing the etiology in patients with partial seziures MRI allows us to determine the migration ubnormalities and demyelinating lesions which could not be shown in CT.

Parsiyel Epilepsilerde Magnetik Rezonans Bulgularý

AMAÇ: Bu çalýşmada parsiyel epilepsi tanýsý olarý 63 hastada Magnetik Rezonans (MR) görüntülemenin etyolojiyi belirlemedeki yeri araştýrýlmýştýr.
MATERYEL VE METOD: Şişli Etfal Hastanesi Nöroloji Kliniði Polikliniðinde parsiyel epilepsi tanýsý ile izlenen 63 hastanýn MR bulgularý retrospektif olarak deðerlendirildi. Hastalardaki nöbet tipleri hem kendilerinden alýnan anamnez, hem de nöbeti yakýndan izlemiş olan kişilerden edinilen bilgiler ýşýðýnda belirlendi. Hastalarýn tümünde elektroansefalografi (EEG) yýlda en az iki kez yinelendi. MR incelemesinde T1, T2 ve proton yoðunluðunda aksiyal,koronal ve sagital kesitler alýndý.
BULGULAR: Hastalarýn 32'si kadýn, 31 tanesi erkek olarak belirlendi. Nöbet tipi 6 hastada basit parsiyel, 14 hastada kompleks parsiyel ve 43 hastada sekonder jeneralize olarak saptandý. Elektroamefalografik (EEG) incelemelerde 47 hastada patoloji bulundu. 16 hastada ise EEG nor­maldi. MR 36 hastada patoloji gösterdi. MR bulgularý 10 hastada arroji, 5 lýastada mu/tipi ak madde lezyonu, 4 has- tada yer kaplayýcý le: ymý, 4 hastada gelişimsel anomali, 3 hastada lýipoksik aýýsejcýlopati, 2 hastada mezial temporal skleroz, 2 hastada ventrikül asimetrisi, 2 hastada eski kalsifiye lezyon, 1 hastada hidrosefali, 1 hastada vasküler lezyon, 1 hastada nörofibromatozis ile uyumlu multipl nodüler ak madde lezyonu olarak sýnýflandýrýldý. Her iki oksipital bölgede az çok simetrik hiperintens iki lezyonu olan hastaya ise kesin taný konulamadý.
SONUÇ: Parsiyel epilepsi tanýsý alanlarda görüntülemede ilk seçilecek yöntem MR olmalýdýr. MR bulgularý, kraniyal bilgisayarlý tomografide (BT) gösterilemeyen migrasyon anmýýa/ileri, mesial temporal skleroz ve demyelinizasyonla giden proçeslerin tanýnmasýna olanak sağlar.