Evaluation of meningococcemia cases hospitalized in pediatric infectious diseases clinic

Objective: To evaluate the relation of mortality and morbidity rates with epidemiologic, clinical and laboratory features of patients with meningococcemia retrospectively.
Material and Method: We reviewed epidemiologic, clinical, laboratory and prognosis of 17 patients hospitalized between january 2004 and december 2006 with meningococcemia according to hospital recordings.
Results: Most patients were hospitalized in summer (%52,9). One patient from the 0-2 age group died. Ten patients had meningococcal meningitidis (%58,8), seven had meningococcemia alone. Three patients had trombocytopenia, 8 had coagulopathy. 2 of 3 patients with both trombocytopenia and coagulopathy and 2 of 3 with leukopenia (<5000/mm3) transfered to intensive care unit (1CU). All patients treatment started in first 24 hours after beginning of symptoms.
Conclusion: Early diagnosis, proper antibiotic and agressive supportive therapy keep importance in meningococcemia. Suspicious cases with meningococcal disease must examined carefully and treatment start rapidly and agressively; if necessary patient transfered to 1CU.

Çocuk enfeksiyon hastalýklarý servisinde izlenen meningokoksemili olgularýmýzýn deðerlendirilmesi

Amaç: Meningokoksemide görülen mortalite ve morbidite oranlarýnýn, hastalarýn epidemiyolojik, klinik ve laboratuar özellikleriyle baðlantýsýný retrospektif olarak deðerlendirmektir.
Araç ve Yöntemler: Ocak 2004 ile Aralýk 2006 tarihleri arasýnda meningokoksemi tanýsý ile yatan 17 hastanýn epidemiyolojik, klinik, laboratuar ve prognozlarý hastane kayýtlarýndan gözden geçirildi.
Bulgular: Hastalarýn çoðu yaz mevsiminde baþvurdu (%52,9). Bir hasta öldü ve ölen hasta 0-2 yaþ grubundaydý. On hastada meningokokal menenjit (%58,8), 7 hastada sadece meningokoksemi (%41,1) vardý. Üç. hastada trombositopeni, 8 hastada koagülopati saptandý. Trombositopeni ve koagülopatinin beraber olduðu 3 hastanýn 2’si ve lökopenisi (<5000/mm3) olan 3 hastanýn 2’ si Yoðun Bakým Ünitesine (YBÜ)’ne sevk edildi. Bütün hastalarýn tedavisi bulgularýn ortaya çýkmasýnýn ilk 24 saatinde baþlandý.
Sonuç: Halen meningokoksemide erken taný, uygun antibiyotik ve agresif destek tedavileri önemini korumaktadýr. Meningokokal hastalýk þüpheli olgularda dikkatli bir klinik deðerlendirme sonrasýnda tedavinin hýzlý ve agresif bir þekilde baþlanmasý ve gereðinde YBÜ’ne transferi yapýlmalýdýr.